Found 12 matching trials
Safety Study of Zinc Finger Nuclease CCR5-modified Hematopoietic Stem/Progenitor Cells in HIV-1 Infected Patients PHASE1 The purpose of the study is to evaluate the safety and feasibility of admin...
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Location
City of Hope Medical Center
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Gene-Modified HIV-Protected Stem Cell Transplant in Treating Patients With HIV-Associated Lymphoma PHASE1 This clinical trial studies gene-modified, human immunodeficiency virus (HI...
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Fred Hutch/University of Washington Cancer Consortium
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EDIT-301 for Autologous Hematopoietic Stem Cell Transplant (HSCT) in Participants With Transfusion-Dependent Beta Thalassemia (TDT) PHASE1 The purpose of this study is to evaluate the safety, tolerability, and effi...
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Active Not Recruiting
Location
University of California San Francisco
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Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell Disease PHASE1 This study is a first-in-human, single-arm, open-label Phase I/II study of ...
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Children's Hospital Los Angeles
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Safety Study of a Dual Anti-HIV Gene Transfer Construct to Treat HIV-1 Infection PHASE1 This is an early phase research study looking at whether an experimental ge...
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Meloxicam vs Placebo for Mobilization PHASE2 This research study is evaluating a drug called meloxicam to see if it prov...
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Massachusetts General Hospital
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Myeloablative Conditioning Orca-T & Allogeneic Donor-Derived CD19/CD22-CAR TCells in B-Cell ALL PHASE1 To assess the safety of administering allogenic, donor-derived CD19/CD22-CA...
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Active Not Recruiting
Location
Stanford Cancer Center
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Immune Tolerance Induction After Liver Transplantation PHASE1 This clinical trial is being conducted to help liver transplant recipients ...
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UCLA Health 200 Medical Plaza
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A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease PHASE1 This is an open label, multicenter, Phase 1/2 study in approximately eight ...
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UCSF Benioff Children's Hospital
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Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft PHASE1 Reduced intensity conditioning (RIC) has emerged and been increasingly adop...
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Location
Stanford University
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